Understanding how the nervous system gives rise to perception, thought, memory, emotion, and action is one of biology’s greatest challenges. Meeting this challenge requires driving scientific breakthroughs that connect discoveries across genes, cells, circuits, and behavior.
Faculty Labs
Bidaye Lab
Bolton Lab
Fitzpatrick Lab
Inagaki Lab
Rangaraju Lab
Stern Lab
Tian Lab
Wang Lab
Yasuda Lab
Labs by Topics
- All Topics
- Addiction
- ALS/ Lou Gherigs Disease
- Alzheimer's Disease/ Dementia
- Anxiety
- Autism Spectrum Disorder
- Biotechnology
- Cellular Function and Communication
- Depression
- Learning and Memory
- Modeling and Computation
- Motivation and Emotion
- Movement Control and Disorders
- Obesity and Eating Disorders
- Parkinson’s Disease
- Schizophrenia
- Sensory Processing and Perception
Neuronal Mechanisms of Episodic Memory
Neuronal Control of Locomotion
Neural Dynamics and Cognitive Functions
Biotechnology for Neural Dynamics and Therapeutics
Neuronal Signal Transduction
Functional Architecture and Development of Cerebral Cortex
Neuroenergetics
Integrative Neural Circuits and Behavior
Disorders of Neural Circuit Function
Recent Discoveries
MPFI seeks to provide a new understanding of the origins, development, and function of the nervous system and its capacity to produce perception, thought, language, memory, emotion, and action.
Recent Papers
Complementary roles of cell-type-specific plasticity in shaping neocortical dynamics for learning action timing
Majumder, S., Hirokawa, K., Yang, Z., Jain, A., Paletzki, R., Gerfen, C. R., Fontolan, L., Romani, S., Yasuda, R., & Inagaki, H. K. (2026). Complementary roles of cell-type-specific plasticity in shaping neocortical dynamics for learning action timing. Nature Communications.
Activity-regulated circSamm50 modulates mitochondrial dynamics and spine structural plasticity
Chanda, K., Bapat, O., Wingfield, J. L., Avchalumov, Y., Kazantzis, M., Carter, J. P., Sharma, N., Davis, R., Yuan, J. X.-J., Rangaraju, V., & Puthanveettil, S. V. (2026). Activity-regulated circSamm50 modulates mitochondrial dynamics and spine structural plasticity. Cell Reports, 45(6).
Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits.
Park, C., Yang, Z., Nashef, A., Gim, J., Bahn, S., Kim, G. H., Zhang, K., Cathala, L., Hong, S., Im, Y., Lee, S.-H., Lee, K., Kim, M.-S., Arnold, D. B., Lee, K. J., Christie, J. M., & Kim, J. S. (2026). Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits. Nature Neuroscience.
argeting the cGAS-STING pathway mitigates Huntington disease pathogenesis in a knock-in mouse model.
Kesharwani, A., Dagar, S., Zuniga, I., Monet, M. C., Halade, G., Upadhyay, G., Nimrod Ramírez-Jarquín, U., Gisselle Lopez-Huerta, V., Mirza, E., Quan, N., & Subramaniam, S. (2026). Targeting the cGAS-STING pathway mitigates Huntington disease pathogenesis in a knock-in mouse model. Proceedings of the National Academy of Sciences of the United States of America, 123(24), e2535879123.
Functional imaging of nine distinct neuronal populations under a miniscope in freely behaving animals.
Phillips, M. L., Urban, N. T., Salemi, T., Dong, Z., & Yasuda, R. (2026). Functional imaging of nine distinct neuronal populations under a miniscope in freely behaving animals. eLife, 15, RP110277.
Central versus peripheral neural control of a coordinated walking pattern in Drosophila
Sapkal, N., Kumar, D. S., Sunke, S., Mancini, N., Pitchford, J., Murakami, K., & Bidaye, S. S. (2026). Central versus peripheral neural control of a coordinated walking pattern in Drosophila. (p. 2026.04.29.721658). bioRxiv.
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